Adverb
Expression
Usually written in kana
1. by all means; at any cost; no matter what; at any rate; surely
その意味をどうしても今、知っておかねばならない。I must know its meaning right now, no matter what.
2. whether (one is) willing or not; willingly or unwillingly; willy-nilly
人と人はどうしてもぶつかるものなんだから。People are bound to clash with each other, after all.
3. on no account; by no means
with. neg. verb
私はどうしても思い出せないんだ。I simply cannot remember it.
4. in the end; in the long run; after all; eventually