1. workmanship; craftsmanship; execution; finish
今回のイラストも、素晴らしい出来でした。The illustration this time was also wonderfully done.
2. grades; results; score; record
テストの出来はどうだ？How did you do on the test?
3. quality (e.g. of a crop)
今年のワインは出来がいいらしい。I hear this year's wine is of good quality.
4. dealings; transactions