regret; remorse; repentance; contrition
deep regret; great sorrow; bitter grief
critical hit; enemy attack dealing heavy damage; devastating blow; crippling strike; crushing damage
grudge; spite; malice; rancor
many regrets; much sadness; much resentment; much bitterness
sensibility; (having) many worries and regrets
grudge of ten years' standing; harbouring a grudge for many years