Verb (5-dan, す, transitive)
1. to melt; to liquefy; to thaw
その事実が、自分の心の中にある氷をまた、少し溶かす。That fact melts the ice in my heart a little more.
2. to dissolve (in a liquid); to bring into solution
こうやって水に溶かすだけなんです。You just dissolve it in water like this.
3. to lose (money; through gambling, etc.); to squander
それなら彼が金を溶かして家賃が払えないのも納得できなくはない。In that case, I can sort of see why he blew his money and can't pay the rent.