1. hole; opening; perforation
also read めど for this sense
2. pit; hollow; hole (in the ground, etc.)
3. burrow; den; lair; holt; hole
4. deficit; shortage; missing person (in a team, meeting, etc.)
5. vacancy; opening
6. flaw
7. well-kept secret place
8. upset victory (with a large payoff)
9. pit (of a theater)
10. hiding place; hideout
11. underbelly (of society, etc.)